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Husband of Isabel.

Born on 10 March 1452 in Sos, in the northwest of the province of Zaragoza in Aragon; died on 23 January 1516 in Madrigalejo.

Enrique IV, El Impotente

Enrique was Isabel’s half-brother, son of Juan II — Isabel’s father — and María of Aragon.

Born on 5 January 1425 in the now-lost Casa de las Aldabas on Calle Teresa Gil in Valladolid; died during the night of 11 to 12 December 1474 in Madrid, possibly by poisoning.

Juana la Beltraneja

Juana was born on 28 February 1462 in Madrid as Juana of Castile, daughter of Queen Juana of Portugal and King Enrique IV. She died on 12 April 1530 in Lisbon. She was Isabel’s rival in the succession to the throne.

Beatriz de Bobadilla

Born around 1440 in Medina del Campo. Isabel’s closest friend.

Juan Pacheco, Marquis of Villena

Pacheco (1419–1474), also known as the Marquis of Villena, was one of the most important noblemen at the court of Castile. He grew up alongside Enrique, who would later become King Enrique IV. He later clashed with Enrique, who had begun favoring Beltrán de la Cueva instead.

Juan II de Castilla

Juan II de Castilla (1405 – 1453) was the father of Isabel. Died when Isabel was only three years old.

Alfonso Carillo. bishop of Toledo

Alfonso Carrillo de Acuña (1413–1482). Nephew of Pacheco. He played an important role in the establishment of the marriage between Isabel and Ferdinand.

Juana I, Daughter of Isabel

Juana was born on 6 November 1479, as the third child of Isabel and Fernando, and is known to us as Juana the Mad.

Álvaro de Luna, statesman

Álvaro de Luna was an influential nobleman at the court of King Juan II de Castilla. He died on 2 June 1453 by beheading in the Plaza Mayor of Valladolid.

Cisneros

Francisco Jiménez de Cisneros was a Spanish statesman under the Catholic Monarchs and a cardinal of the Roman Catholic Church.